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Post-transplant Long-term Complications

3. A 39-year-old CKD 5 secondary to HIV associated nephropathy had a deceased donor kidney transplantation. CD4 count is 250/ml and receiving HAART. Currently she is on Tacrolimus-based triple immunosuppression. Her kidney function has improved and started to pass more urine. She presented with 2 weeks history of non-productive cough, low grade temperature (37.5 °C). She has dyspnoea on excretion (respiratory rate at rest is 20/min) but chest X-Ray reported normal. Clinically there were few physical findings only few scattered wheezes. Sat 100% on air and desaturates to 95% on exertion.
18
Feb
177

What is the differential diagnosis? How do you manage this case?

Posted in: Post-transplant Long-term Complications , Week 5 ,
2. A 61-year-old CKD 5 secondary to diabetic nephropathy had a deceased donor kidney transplantation. Currently she is on Tacrolimus-based triple immunosuppression. Her kidney function has improved and started to pass more urine. On day 11 she developed dry cough, low grade temperature (37.8 °C). Clinically there were very few physical findings only of few scattered crepes. She has dyspnoea (respiratory rate is 38/min) but chest X-Ray showed bilateral perihilar infiltrates (see below). CT chest showed ground glass appearance. Blood gas showed PaO2 of 8 kPa and picture of compensated respiratory alkalosis.
18
Feb
194

What is the differential diagnosis? How do you manage this case?

Posted in: Post-transplant Long-term Complications , Week 5 ,
1. A 65-year-old man was admitted with a fever (38 °C) and non-productive (dry) cough 4 months after cadaveric transplantation. CMV negative to CMV positive recipient. Oxygen saturation on air was reported at 89%. CXR is shown below:
18
Feb
259

What is your differential diagnosis? How do you manage this case?

Posted in: Post-transplant Long-term Complications , Week 5 ,
Pneumocystis Pneumonia in SOT – Discussion
18
Feb
40
Posted in: Post-transplant Long-term Complications , Week 5 ,
V. Intravenous immunoglobulin as a preventive strategy against BK virus viremia and BKV-associated nephropathy in kidney transplant recipients—Results from a proof-of-concept study
11
Feb
71

Please summarise this article. What are the other uses of IVIG in transplantation? View / Download

Posted in: Post-transplant Long-term Complications , Week 4 ,
IV. BK Virus Nephropathy in Kidney Transplantation: A State-of-the-Art Review
11
Feb
88

Please summarise this article. View / Download

Posted in: Post-transplant Long-term Complications , Week 4 ,
III. BK polyomavirus infection promotes growth and aggressiveness in bladder cancer
11
Feb
85

Please summarise this article. What is the level of evidence provided by this article? What are the weaknesses and strengths of this article? Please summarise this article. View / Download

Posted in: Post-transplant Long-term Complications , Week 4 ,
II. Role of BK human polyomavirus in cancer
11
Feb
93

Please summarise this article. What is the level of evidence provided by this article? View / Download

Posted in: Post-transplant Long-term Complications , Week 4 ,
I. Update on the Management of BK Virus Infection
11
Feb
117

Please summarise this article. What is the level of evidence provided by this article? View / Download

Posted in: Post-transplant Long-term Complications , Week 4 ,
5. A 31-years old renal transplant recipient developed this lesion in his anal region 4 years after successful treatment of acute AMR. He is currently on Tacrolimus (trough 8 ng/ml), MMF 750 mg bd and prednisolone 5 mg od. The lesion is itchy.
11
Feb
122

What is your differential diagnosis? What do you confirm the diagnosis? What is the treatment? Does this condition affect other parts of the body? What are the clinical presentations of this disease?

Posted in: Post-transplant Long-term Complications , Week 4 ,